Small-Volume Resuscitation from Hemorrhagic Shock by Hypertonic Saline Dextran – Conceptional Basis and Historical Background
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چکیده
منابع مشابه
Small-volume resuscitation from hemorrhagic shock by hypertonic saline dextran -- conceptional basis and historical background.
Early and adequate fluid resuscitation is essential for the survival of the severely hypovolemic trauma patient. Studies have shown that, besides age, severity of injury and arterial hypotension, the duration of shock is the most important factor influencing the recovery from multiple trauma [1]. While for optimal resuscitation rapid restoration of blood volume is essential, the lack of compati...
متن کاملHypertonic Saline Dextran Ameliorates Organ Damage in Beagle Hemorrhagic Shock
OBJECTIVE The goal of this study was to investigate the effect of hypertonic saline with 6% Dextran-70 (HSD) resuscitation on organ damage and the resuscitation efficiency of the combination of HSD and lactated ringers (LR) in a model of hemorrhage shock in dogs. METHODS Beagles were bled to hold their mean arterial pressure (MAP) at 50 ± 5 mmHg for 1 h. After hemorrhage, beagles were divided...
متن کاملSmall volume hypertonic resuscitation of circulatory shock.
Small volume hypertonic resuscitation is a relatively new conceptual approach to shock therapy. It was originally based on the idea that a relatively large blood volume expansion could be obtained by administering a relatively small volume of fluid, taking advantage of osmosis. It was soon realized that the physiological vasodilator property of hypertonicity was a useful byproduct of small volu...
متن کاملAdministration of Large Volume Hypertonic Solutions for Resuscitation of Hemorrhagic Shock in Rabbit
An animal model was designed to study the effect of large volume Hypertonic Solutions (HTS) for resuscitation following a hypovolemic shock. Resuscitation in hypovolemic animals was performed by infusion of 15 ml/kg of normal saline (group I), 5% sodium bicarbonate (NaHCO3) (group II), 5% sodium chloride (NaCI) and 7.5 % NaHCO3 1:1 VN (group III), 5% NaC1 (group IV), and 5% NaCl and 5% serum a...
متن کاملHypertonic saline solutions in shock resuscitation.
Hypertonic saline solutions (HSS) have several characteristics that may improve the survival of patients during the initial treatment of certain types of shock. The use of isotonic crystalloids for resuscitation has several limitations: large infusion volumes are needed to increase the intravascular space; these large volumes cannot be given rapidly; and the fluid rapidly redistributes througho...
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ژورنال
عنوان ژورنال: European Surgical Research
سال: 2002
ISSN: 0014-312X,1421-9921
DOI: 10.1159/000048900